EFMC-ISMC 2018

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Late abstract submission is open until August 31!


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Conferences > Archives > EFMC-ISMC 2018

Confirmed Speakers


Award & Prize Lectures

Prof. Benjamin CRAVATT
Prof. Benjamin CRAVATT
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, United States
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PROUS INSTITUTE-OVERTON AND MEYER AWARD FOR NEW TECHNOLOGIES IN DRUG DISCOVERY
Activity-Based Proteomics - Protein and Ligand Discovery on a Global Scale

Prof. Christa MÜLLER
Prof. Christa MÜLLER
UNIVERSITY OF BONN, Bonn, Germany
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NAUTA AWARD FOR PHARMACOCHEMISTRY
Tools and Drugs for Purine Targets - Important Players in Inflammation and Cancer

Prof. Adam NELSON
Prof. Adam NELSON
UNIVERSITY OF LEEDS, Leeds, United Kingdom
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UCB-EHRLICH AWARD FOR EXCELLENCE IN MEDICINAL CHEMISTRY
How Best to Discover Bioactive Small Molecules?

Plenary Lectures

Dr Diego ARDIGO
Dr Diego ARDIGO
CHIESI GROUP, PARMA, Italy
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The Therapeutic Challenge of the New Era: Developing and Making Available Life Changing Treatment to Patients with Rare Diseases

Prof. Tatjana AVSIC-ZUPANC
Prof. Tatjana AVSIC-ZUPANC
UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia
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Zika Virus: An Old Virus with a New Face

Prof. Benjamin DAVIS
Prof. Benjamin DAVIS
OXFORD UNIVERSITY, Oxford, United Kingdom
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Sugars & Proteins: Glycomimetics to Target Infectious Disease

Dr Bayard HUCK
Dr Bayard HUCK
MERCK BIOPHARMA, Darmstadt, Germany
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It’s a Small-Molecule World: Medicinal Chemistry Challenges and Opportunities for the Next Decade

Prof. Cristina NEVADO
Prof. Cristina NEVADO
UNIVERSITY OF ZURICH, Zurich, Switzerland
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Smart Chemical Probes: from Bromodomain Ligands to Natural Products

Dr Helga RÜBSAMEN-SCHAEFF
Dr Helga RÜBSAMEN-SCHAEFF
AICURIS GMBH & CO. KG, Wuppertal, Germany

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Development of Non-Nucleosidic Compounds against DNA Viruses of the Herpes Group. The Era After Nucleosides: Letermovir and Pritelivir

Prof. Peter H. SEEBERGER
Prof. Peter H. SEEBERGER
MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES, Berlin, Germany
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Synthetic Glycoconjugate Vaccines against Bacterial Infections

Invited Speakers

Prof. Andrea ABLASSER
Prof. Andrea ABLASSER
EPFL, Lausanne, Switzerland
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Intracellular DNA Sensing in Health and Disease

Prof. Andreas BENDER
Prof. Andreas BENDER
UNIVERSITY OF CAMBRIDGE, Cambridge, United Kingdom
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Beyond Single-Target Activities: Using Polypharmacology and Systems Readouts for Compound Selection and Mode-of-Action Analysis

Dr Jonas BOSTRÖM
Dr Jonas BOSTRÖM
ASTRAZENECA, Mölndal, Sweden
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Stuck in a Rut with Old Chemistry

Dr Giovanni BOTTEGONI
Dr Giovanni BOTTEGONI
HEPTARES THERAPEUTICS, Welwyn Garden City, United Kingdom
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In silico Polypolpharmacology

Dr Cedric BOULARAN
Dr Cedric BOULARAN
INVIVOGEN, Toulouse, France
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Use of Cyclic Dinucleotides (CDNs) to Induce Stimulator of Interferon Genes (STING)-Dependent Antitumor Immunity

Prof. Christina CHAI
Prof. Christina CHAI
NATIONAL UNIVERSITY OF SINGAPORE, Singapore, Singapore
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Towards the Development of Novel Inhibitors for Chikungunya Virus Infection: Approaches in Structure-Activity-Metabolism Relationship (SAMR) Studies

Dr Philip CHAMBERLAIN
Dr Philip CHAMBERLAIN
CELGENE, Alameda, United States
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Targeting 'Undruggable' Transcription and Translation Factors for Degradation with Low Molecular Weight Cereblon Modulators

Prof. Steven CHARLTON
Prof. Steven CHARLTON
UNIVERSITY OF NOTTINGHAM, Nottingham, United Kingdom
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"Micro-Pharmacokinetics”: How Local Drug Concentration Influences Observed Binding Kinetics

Prof. Fener CHEN
Prof. Fener CHEN
FUDAN UNIVERSITY, Shanghai Shi, China
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Asymmetric Synthesis of Statin API as the Hypolipidemic Agents: The Evolution from the Chemical Kinetic Resolution to the Asymmetric Catalytic Technology (An Odessy)

Dr Diane COE
Dr Diane COE
GLAXOSMITHKLINE, Stevenage, United Kingdom
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Modification of Cyclic Dinucleotides to Enhance Modulation of the Innate Immune Response

Dr Liesbeth DE LANGE
Dr Liesbeth DE LANGE
UNIVERSITY OF LEIDEN, Leiden, The Netherlands
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Target Binding Kinetics and its Relevance in the in vivo Context

Prof. Bernard FLYNN
Prof. Bernard FLYNN
MONASH UNIVERSITY, Parkville, Australia
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Unravelling the Mysteries of the Sphinx: Novel Targets and Small-Molecule Therapeutics from the Sphingolipid Synthesis and Signaling Pathway

Prof. Karl GADEMANN
Prof. Karl GADEMANN
UNIVERSITY OF ZURICH, Zurich, Switzerland
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Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis

Prof. Antony GEE
Prof. Antony GEE
KING'S COLLEGE LONDON, London, United Kingdom
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PET Molecular Imaging – an Overview

Dr Riccardo GIOVANNINI
Dr Riccardo GIOVANNINI
BOEHRINGER INGELHEIM, Biberach, Germany
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First Time Disclosure of BI 409306, a First in Class PDE9 Inhibitor for the Treatment of CNS Diseases

Prof. Stanislav GOBEC
Prof. Stanislav GOBEC
UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia
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Nonpeptidic Selective Inhibitors of Immunoproteasome

Dr Stephanie GUERET
Dr Stephanie GUERET
ASTRAZENECA-MAX PLANCK INSTITUTE SATELLITE UNIT, Dortmund, Germany
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Novel Hybrid Macrocyclic Modalities for Structure-Based Protein Mimetics

Dr Michael G. HAHN
Dr Michael G. HAHN
BAYER HEALTHCARE, Wuppertal, Germany
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Discovery of a Novel Oral NO- and Heme-Independent sGC Activator BAY 1101042

Dr Laura HEITMAN
Dr Laura HEITMAN
UNIVERSITY OF LEIDEN, Leiden, The Netherlands
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Allosteric Modulation of the mGlu2 Receptor: from Structure-Kinetic Relationships to in vivo Efficacy
(2017 MedChemComm Emerging Investigator Lectureship)

Dr Jesus JIMENEZ-BARBERO
Dr Jesus JIMENEZ-BARBERO
CIC BIOGUNE, Derio, Spain
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Breaking the Limits in Analyzing Carbohydrate Recognition by NMR


Prof. Stefan KRAUSS
UNIVERSITY OF OSLO, Oslo, Norway

Tankyrase Inhibitor Development: Evidence for Potential in Cancer Immune Therapy

Dr Jesper LAU
Dr Jesper LAU
NOVO NORDISK, Maaloev, Denmark
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The Discovery of Semaglutide - A Journey from Ala Scan to Structural Design of GLP-1 Analogues

Prof. Stefan LAUFER
Prof. Stefan LAUFER
UNIVERSITY OF TÜBINGEN, Tübingen, Germany
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EGFR Triple Mutant L858R_T790M_ C797S Recent Set-Backs and New Hope in Fighting Mutant Non-Small Cell Lung Cancer

Dr David E. LEAHY
Dr David E. LEAHY
THE DISCOVERY BUS LTD, Macclesfield, United Kingdom
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Artificial Intelligence. Not Just Another Name for in Silico Design

Dr Mark J. MILLAN
Dr Mark J. MILLAN
INSTITUT DE RECHERCHES SERVIER, Croissy-sur-Seine, France
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Multi-Functional Treatments for Multi-Factorial Neurodegenerative Disorders: the Challenge of Alzheimer's Disease

Dr Laurence MULARD
Dr Laurence MULARD
INSTITUT PASTEUR, Paris, France
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A Multidisciplinary Strategy to Synthetic Carbohydrate-Based Conjugates for Vaccination against Shigella: from Concept to First-in-Human Study

Dr Mikihiko NAITO
Dr Mikihiko NAITO
NATIONAL INSTITUTE OF HEALTH SCIENCES, Tokyo, Japan
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Recent Advances in Bifunctional Degrader Molecules (e.g. SNIPER) for Targeted Protein Degradation via the Ubiquitin Proteasome System; Status and Outlook

Prof. Hermen OVERKLEEFT
Prof. Hermen OVERKLEEFT
LEIDEN UNIVERSITY, Leiden, The Netherlands
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Activity-Based Glycosidase Profiling in Biomedicine and Biotechnology

Prof. Roberto PELLICCIARI
Prof. Roberto PELLICCIARI
TES PHARMA SRL, Corciano, Italy
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Obeticholic Acid, Leading in the NASH Race. History and Perspectives

Dr Robert PULZ
Dr Robert PULZ
NOVARTIS PHARMA, Basel, Switzerland
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Discovery of LOU064, a Covalent BTK Inhibitor with Best in Class Selectivity

Dr Laura QUARANTA
Dr Laura QUARANTA
SYNGENTA AG, Basel, Switzerland
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Synthesis and Fungicidal Activity of a New Family of Oxysterol Binding Protein Inhibitors

Dr Murali RAMACHANDRA
Dr Murali RAMACHANDRA
AURIGENE DISCOVERY TECHNOLOGIES LTD, Bangalore, India
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Small Molecule Immune Checkpoint Antagonists for Cancer Therapy

Dr Hasane RATNI
Dr Hasane RATNI
F. HOFFMANN-LA ROCHE LTD, Basel, Switzerland
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Discovery of RG7916, a Selective SMN2 Splicing Modifier for the Treatment of Spinal Muscular Atrophy

Dr Joachim RHEINHEIMER
Dr Joachim RHEINHEIMER
BASF, Ludwigshafen am Rhein, Germany
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Natural Products as Leads in Agrochemistry

Dr Raphaël RODRIGUEZ
Dr Raphaël RODRIGUEZ
INSTITUT CURIE, Paris, France
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An Iron Hand over Cancer Stem Cells

Dr Webster L. SANTOS
Dr Webster L. SANTOS
VIRGINIA TECH, Blacksburg, United States
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Controlling Sphingosine-1-Phosphate Levels as a Therapeutic Strategy

Dr Laurent SCHIO
Dr Laurent SCHIO
SANOFI, Vitry sur Seine, France
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Design and Rationale for Exquisite Selectivity of Preclinical and Clinical Kinase Inhibitors

Dr Magnus SCHOU
Dr Magnus SCHOU
KAROLINSKA INSTITUTE, Stockholm, Sweden
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PET in Neuroscience Drug Discovery and Development


Mr Marwin SEGLER
BENEVOLENTAI, London, United Kingdom

Computer-Aided Synthesis Planning

Prof. David SELWOOD
Prof. David SELWOOD
UNIVERSITY COLLEGE LONDON, London, United Kingdom
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C-Natruiretic Peptide Agonists for Cardiovascular Disease

Prof. Satoshi SHUTO
Prof. Satoshi SHUTO
HOKKAIDO UNIVERSITY, Sapporo, Japan
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Design and Synthesis of Congerners of Cyclic ADP-Ribose, a Ca2+-Mobilizing Second Messenger, Toward Identification of the Target Protein

Prof. Richard B. SILVERMAN
Prof. Richard B. SILVERMAN
NORTHWESTERN UNIVERSITY, Evanston, United States
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Design, Synthesis, and Mechanism of β-Glucocerebrosidase Activators for Gaucher’s and Parkinson’s Diseases

Prof. Jurij SVETE
Prof. Jurij SVETE
UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia
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New Chemical Libraries in Exploration of Chemical Space

Dr Nick TERRETT
Dr Nick TERRETT
MERCK SHARP & DOHME RESEARCH GMBH (MSD), Kriens, Switzerland
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Cell Permeability with Beyond ‘Rule of 5’ Modalities – Do We Understand How This Works?

Dr Martin K. THOMSEN
Dr Martin K. THOMSEN
AARHUS UNIVERSITY, Aarhus C, Denmark
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In vivo Anti-Viral and -Tumor Effect Of 3’3’-cAIMP STING Activation

Dr Nicolas THOMÄ
Dr Nicolas THOMÄ
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH, Basel, Switzerland
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The Zinc-Degrome

Dr Jan Willem THURING
Dr Jan Willem THURING
JANSSEN PHARMACEUTICA NV, Beerse, Belgium
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Discovery of JNJ-64619178 as a Potent and Selective PRMT5 Inhibitor for the Treatment of Lung and Hematologic Cancers

Prof. Peter TIMMERMAN
Prof. Peter TIMMERMAN
PEPSCAN THERAPEUTICS, Lelystad, The Netherlands
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Tricyclic Peptides via Templated Tandem CLIPS/CUAAC Cyclizations

Prof. Matthew TODD
Prof. Matthew TODD
UNIVERSITY COLLEGE LONDON, London, United Kingdom
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All Bugs are Shallow: Open Source Drug Discovery

Dr Gergely TOTH
Dr Gergely TOTH
CANTABIO PHARMACEUTICALS INC., Sunnyvale, United States
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Targeting the Monomeric Intrinsically Disordered Structural State of Tau and Alpha-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Alzheimer's and Parkinson’s Disease

Dr Wes TROTTER
Dr Wes TROTTER
MSD, Boston, United States
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Cyclic Dinucleotide STING Agonists as Anti-Tumor Agents

Dr David TULLY
Dr David TULLY
NOVARTIS, Emeryville, United States
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Discovery of LJN452 (Tropifexor), a Highly Potent, Non-Bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and NASH

Dr Sean C. TURNER
Dr Sean C. TURNER
ABBVIE, Ludwigshafen am Rhein, Germany
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Positive Allosteric Modulators of the GABA-B Receptor

Dr Anne VALADE
Dr Anne VALADE
UCB, Braine-l'Alleud, Belgium
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The Value of Orthogonal Techniques for Elucidating Binding Site(s) of GPCR Allosteric Modulators: a Case Study With Positive Allosteric Modulators of Dopamine Receptors

Dr Eric VALEUR
Dr Eric VALEUR
ASTRAZENECA, IMED BIOTECH UNIT, Gothenburg, Sweden
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New Modalities for Complex and Unprecedented Biological Targets

Dr Willem VAN HOORN
Dr Willem VAN HOORN
EXSCIENTIA, Dundee, United Kingdom
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Re-Energising Small Molecule Drug Discovery

Prof. Dmytro VOLOCHNYUK
Prof. Dmytro VOLOCHNYUK
ENAMINE LTD, Kyiv, Ukraine
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Synthesis of MedChem-Relevant Gem-Difluorocycloalkane Building Blocks

Dr Franz VON NUSSBAUM
Dr Franz VON NUSSBAUM
BAYER, Monheim, Germany

A New Target in Fungal Protein Biosynthesis: Shared Learnings for AgChem and MedChem

Prof. Hans WANDALL
Prof. Hans WANDALL
UNIVERSITY OF COPENHAGEN, Copenhagen, Denmark
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Targeting of Cancer Specific Glycopeptide Epitopes

Dr Sven WEILER
Dr Sven WEILER
BASILEA PHARMACEUTICA INTERNATIONAL LTD., Basel, Switzerland
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Active Site Inhibitors of Sphingosine 1-Phosphate Lyase - Exploring Novel Biology with Tool Compounds

Prof. Bert WINDHORST
Prof. Bert WINDHORST
VU UNIVERSITY MEDICAL CENTER, Amsterdam, The Netherlands
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PET for Oncology Drug Discovery and Development

Dr Wolfgang WRASIDLO
Dr Wolfgang WRASIDLO
UNIVERSITY OF CALIFORNIA SAN DIEGO, La Jolla, United States
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Discovery of Peptidomimetics Targeting Protein-Protein Interactions of Alpha-Synuclein

Prof. Hang YIN
Prof. Hang YIN
TSINGHUA UNIVERSITY, Beijing, China
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Small Molecule Immunomodulators that Target Toll-Like Receptors

Prof. Xumu ZHANG
Prof. Xumu ZHANG
SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY, Guangdong, China
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Practical Asymmetric Hydrogenation

Prof. Markus ZWECKSTETTER
Prof. Markus ZWECKSTETTER
MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY, Göttingen, Germany
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Understanding Aggregation Inhibition of Alpha-Synuclein and Tau by Small Molecules

Oral Communications

Dr Amjad ALI
Dr Amjad ALI
MERCK, SHARP & DOHME, Kenilworth, United States
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Discovery and Clinical Evaluation of MK-8150, a Novel Nitric Oxide Donor with a Unique Mechanism of Nitric Oxide Release

Dr Steve ANDREWS
Dr Steve ANDREWS
UNIVERSITY OF CAMBRIDGE, Cambridge, United Kingdom
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Brain-Penetrant Autophagy Modulators for Treating Neurodegenerative Diseases

Dr Bernard BARLAAM
Dr Bernard BARLAAM
ASTRAZENECA, Cambridge, United Kingdom
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Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 that Enables Transient Target Engagement for the Treatment of Haematological Malignancies

Dr Stefan BÄURLE
Dr Stefan BÄURLE
BAYER AG, Berlin, Germany
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First Disclosure of the Clinical Candidate BAY-840, a Potent And Selective hBradykinin B1 Antagonist for the Treatment of Chronic Inflammatory Diseases, Generated within the Bayer-Evotec Strategic Alliance

Dr Jose CID
Dr Jose CID
JANSSEN R&D, Toledo, Spain
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Metabotropic Glutamate Receptor Type 2 Positive Allosteric Modulators (mGlu2 Receptor PAMS) as a Transformational Epilepsy Treatment

Prof. Gabriele COSTANTINO
Prof. Gabriele COSTANTINO
UNIVERSITY OF PARMA, Parma, Italy
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Targeting Non Essential Bacterial Targets as a Novel Route to Counteract Bacterial Resistance

Dr Marton CSEKEI
Dr Marton CSEKEI
SERVIER RESEARCH INSTITUTE OF MEDICINAL CHEMISTRY, Budapest, Hungary
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EFMC Prize for a Young Medicinal Chemist in Industry
The Challenges of Restoring Programmed Cell Death Through MCL1 Inhibition

Dr Vincent DARMENCY
Dr Vincent DARMENCY
AC IMMUNE SA, Lausanne, Switzerland
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Discovery of Candidates for PET Molecular Imaging of Pathological TDP-43 Aggregates in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis Patients

Ms Ana Rita DE CARVALHO ACURCIO
Ms Ana Rita DE CARVALHO ACURCIO
UNIVERSITY OF LISBON, Lisbon, Portugal
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New Small-Molecule Immune Checkpoint Inhibitors: A Step Forward in Cancer Immunotherapy

Dr Al DOSSETTER
Dr Al DOSSETTER
MEDCHEMICA LIMITED, Macclesfield, United Kingdom
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Potency and Patents, New Arenas for Matched Molecular Pair Analysis in the AI World

Prof. Maria DUCA
Prof. Maria DUCA
UNIVERSITÉ CÔTE D'AZUR, Nice, France
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Synthetic Small-Molecule RNA Ligands: Scope and Therapeutic Applications

Dr Peter ETTMAYER
Dr Peter ETTMAYER
BOEHRINGER-INGELHEIM, Vienna, Austria
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Chemical Probes for New Therapeutic Concept Discovery

Dr Esther FERNANDEZ
Dr Esther FERNANDEZ
GLAXOSMITHKLINE, Tres Cantos, Spain
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Identification of New Antimalarial GSK607: An Example of Adaptive and Differentiated Early Drug Development

Prof. Paul FISH
Prof. Paul FISH
ARUK UCL DRUG DISCOVERY INSTITUTE, London, United Kingdom
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Development of Potent, Selective, CNS Penetrant Small Molecule Inhibitors of Notum to Potentiate Wnt Signaling for the Maintainance of Synaptic Function in Alzheimer’s Disease

Dr Carles GALDEANO
Dr Carles GALDEANO
UNIVERSITY OF BARCELONA, Barcelona, Spain
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Drugging the Fbw7 E3 Ligase with a Combined Computational and Biophysical Approach

Dr Matthias GEHRINGER
Dr Matthias GEHRINGER
UNIVERSITY OF TUEBINGEN, Tuebingen, Germany
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Buruli Ulcer and the mTOR Pathway: Total Synthesis, Structure-Activity and Target Elucidation Studies of Mycolactones

Ms Victoria GEORGI
Ms Victoria GEORGI
BAYER AG, Berlin, Germany
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Large-Scale Analysis of Kinase Inhibitors' Target Binding Kinetics and its Implications for Drug Discovery

Dr Brian GERSTENBERGER
Dr Brian GERSTENBERGER
PFIZER, Cambridge, United States
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Discovery of the TYK2 Selective Inhibitor PF-6826647 for the Treatment of Crohn’s Disease, and Other Autoimmune Conditions

Prof. Antimo GIOIELLO
Prof. Antimo GIOIELLO
UNIVERSITY OF PERUGIA, Perugia, Italy
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Integrated System for the Expedited Generation and Characterization of Drug-Like Libraries for Hit-to-Lead Explorations

Dr Peter GROOTENHUIS
Dr Peter GROOTENHUIS
VERTEX PHARMACEUTICALS, San Diego, United States
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IUPAC-Richter Prize Lecture
Discovery of CFTR Modulators For The Treatment of Cystic Fibrosis

Dr Steven HOWARD
Dr Steven HOWARD
ASTEX THERAPEUTICS , Cambridge , United Kingdom
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ASTX660, the First Fragment-Derived IAP Antagonist in the Clinic

Prof. James JANETKA
Prof. James JANETKA
WASHINGTON UNIVERSITY IN SAINT LOUIS, Saint Louis, United States
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Glycoside Antagonists of Bacterial Lectins: New Treatment Options for Recurrent and Antibiotic Resistant UTI

Dr Allan JORDAN
Dr Allan JORDAN
CANCER RESEARCH UK MANCHESTER INSTITUTE, Manchester, United Kingdom
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Discovery of First-in Class, Selective and Noncovalent Small Molecule Inhibitors of DNMT1

Dr Jamie KNIGHT
Dr Jamie KNIGHT
CHARLES RIVER, Harlow, United Kingdom
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Discovery of GDC-0077: A Highly Selective Inhibitor and Degrader of Mutant PI3K-Alpha

Dr Rainer MACHAUER
Dr Rainer MACHAUER
NOVARTIS PHARMA AG, Basel, Switzerland
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The Discovery of CNP520, an Amino-1,4-Oxazine BACE Inhibitor in Prevention Studies

Dr Daniel MERK
Dr Daniel MERK
ETH ZÜRICH, Zürich, Switzerland
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A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase to Treat Non-Alcoholic Steatohepatitis
(EFMC-YMCS Presentation Prize)

Ms Anna MIGGLAUTSCH
Ms Anna MIGGLAUTSCH
TU GRAZ, Graz, Austria
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Development of Small-Molecule Inhibitors of Adipose Triglyceride Lipase (ATGL)

Mr Andrew MONTGOMERY
Mr Andrew MONTGOMERY
UNIVERSITY OF WOLLONGONG, Wollongong, Australia
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Development of Novel Sialyltransferase Inhibitors via Computer Aided Drug Design

Dr Christian OTTMANN
Dr Christian OTTMANN
EINDHOVEN UNIVERSITY OF TECHNOLOGY, Eindhoven, The Netherlands
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Small-Molecule Stabilization of Protein-Protein Interactions by Natural Products, Supramolecular Ligands, Fragments and Macrocycles

Dr Vladimir A. PALYULIN
Dr Vladimir A. PALYULIN
LOMONOSOV MOSCOW STATE UNIVERSITY, Moscow, Russia
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AMPA Receptor Positive Allosteric Modulators Based on New Scaffolds: Design, Synthesis, and Studies

Mr Tamas REVESZ
Mr Tamas REVESZ
BIOLOGICAL RESEARCH CENTRE, HUNGARIAN ACADEMY OF SCIENCES, Szeged, Hungary
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Charting the Structure-Resistance Landscape of Novel Antibiotics

Dr Shabnam SHAABANI
Dr Shabnam SHAABANI
UNIVERSITY OF GRONINGEN, Groningen, The Netherlands
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Small Molecules Inhibiting PD1-PDL1 Immune Checkpoint

Dr Hong SHEN
Dr Hong SHEN
ROCHE INNOVATION CENTER, Shanghai, China
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Anti-HBV Drug Discovery Enabled by Structure-Based Drug Design and Phenotypic Screening

Dr Alice SOSIC
Dr Alice SOSIC
UNIVERSITY OF PADOVA, Padova, Italy

Mechanisms of HIV-1 Nucleocapsid Protein Inhibition by Small Molecules Targeting RNA

Dr Hauke SZILLAT
Dr Hauke SZILLAT
SANOFI, Frankfurt, Germany
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Discovery and Optimization of Non-Covalent, Selective, and Bioavailable Small Molecule Inhibitors of the KEAP1-Nrf2 Pathway

Dr Alexander TITZ
Dr Alexander TITZ
HELMHOLTZ INSTITUTE FOR PHARMACEUTICAL SCIENCES, Saarbrücken, Germany
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EFMC Prize for a Young Medicinal Chemist in Academia
Carbohydrate-binding Proteins as Targets for Anti-Infectives and Diagnostics: ESKAPE pathogen Pseudomonas aeruginosa and its Lectins

Dr Juraj VELCICKY
Dr Juraj VELCICKY
NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, Basel, Switzerland
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Discovery of SPL-707: A Potent, Selective, and Orally Bioavailable SPPL2a Inhibitor

Dr Fredrik ZETTERBERG
Dr Fredrik ZETTERBERG
GALECTO BIOTECH, Gothenburg, Sweden
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The First Class of Orally Available Mono-Saccharide Galectin-3 Inhibitors for Treatment of Fibrosis (NASH) and Cancer


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