7th NovAliX Conference

Confirmed Speakers


Keynote Speakers

Structure-biophysics Driven PROTAC Design for Degrading Undruggable Cancer Targets (KL01)
Prof. Alessio CIULLIProf. Alessio CIULLI
(UNIVERSITY OF DUNDEE, Dundee, United Kingdom)

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From Fragments to Pharmaceuticals (KL02)
Dr Harren JHOTIDr Harren JHOTI
(ASTEX PHARMACEUTICALS, Cambridge, United Kingdom)

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Session 1: Recent Advances in FBDD

Enabling Drug Discovery with Crude Reaction Mixture Screening (IL03)
Dr Ben DAVISDr Ben DAVIS
(VERNALIS RESEARCH, Cambridge, United Kingdom)

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PhABits – Shining New Light on Fragments Approaches for Assessing Targets Tractability (IL01)
Dr Mike HANNDr Mike HANN
(GSK MEDICINES RESEARCH CENTRE, Stevenage, United Kingdom)

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Ligand-Based Fluorine NMR Screening in Drug Discovery (IL02)
Dr Anna VULPETTIDr Anna VULPETTI
(NOVARTIS, Basel, Switzerland)

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Session 2: Challenging Targets (GPCRs, Ion Channels...)

Advancing Cryo-EM for Determination of G Protein-Coupled Receptor Structure (IL05)
Prof. Patrick M. SEXTONProf. Patrick M. SEXTON
(MONASH UNIVERSITY, Parkville, Australia)

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Structural Biology of Seven-Transmembrane Receptors Toward Drug Discovery (IL04)
Prof. Shigeyuki YOKOYAMAProf. Shigeyuki YOKOYAMA
(RIKEN, Yokohama City, Japan)

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Session 3: Cryo-EM in Drug Discovery

Advancing Drug Discovery in Pharma Using Cryo-EM (IL06)
Dr Claudio CIFERRIDr Claudio CIFERRI
(GENENTECH, South San Francisco, United States)

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Session 4: X-ray Crystallography / Cryo-EM Complementarity

Increased Performance in High-Throughput Compound and Fragment Screening Campaigns by the Use of "Club Class" Data Collection (IL07)
Dr Gerard BRICOGNEDr Gerard BRICOGNE
(GLOBAL PHASING LTD., Cambridge, United Kingdom)

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Applying Hybrid Biophysical and Structural Methods to Study Allosteric Regulation of GTP Cyclohydrolase I - A Target for Treating Inflammatory and Neuropathic Pain (IL09)
Dr Herbert NARDr Herbert NAR
(BOEHRINGER INGELHEIM, Biberach, Germany)

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Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase (IL08)
Prof. Holger STARKProf. Holger STARK
(MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY, Göttingen, Germany)

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Session 5: Hot Topics

Re-energizing Small Molecule Drug Discovery by Centaur Chemist™ (IL10)
Dr Daisuke TANAKADr Daisuke TANAKA
(EXSCIENTIA, Osaka, Japan)

Organised by

With the support of

The Pharmaceutical Society of Japan Division of Medicinal Chemistry

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