Confirmed Speakers

Daniel G. Bracewell is Professor of Bioprocess Analysis at the UCL Department of Biochemical Engineering. He has made major contributions to the fundamental understanding of biopharmaceutical purification operations, including collaborations with Thailand, India and the USA. He has authored more than 90 peer reviewed journal articles in the area to date and currently supervises 15 doctoral and postdoctoral projects, many of these studies are in collaboration with industry. One such project was the basis from which the spinout Puridify a nanofibre absorption technology company was created. He is academic lead for the UCL-Pall Biotech Centre of Excellence.

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Giorgio Carta received his PhD in Chemical Engineering from the University of Delaware in 1984 and is currently the Lawrence R. Quarles Professor in the Department of Chemical Engineering at the University of Virginia. He has published extensively in the area of adsorption and ion exchange with emphasis on protein chromatography. He has co-authored the book “Protein Chromatography – Process Development and Scale-Up," Wiley-VCH, 1st ed. 2010, 2nd ed. 2020, has served as section co-editor of Section 16 “Adsorption and Ion Exchange” of Perry's Chemical Engineers' Handbook, 7th, 8th, and 9th edition, and authored the textbook "Heat and Mass Transfer for Chemical Engineers: Principles and Applications," McGraw-Hill, 2021. He has served as member of the Organizing Committee of PREP International Symposium, Exhibit & Workshops on Preparative and Process Chromatography since 1997 and as Chair of the PREP Symposium annually since 2009. He is also involved extensively in professional education in the field of protein chromatography, including leading a short course in protein chromatography held twice a year at the University of Virginia. Giorgio Carta is an Editor of Biotechnology Journal and a member of the Editorial Board of Separation Science & Technology. He is a consultant for a number of chemical and pharmaceutical companies.

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With a Ph. D. in organic chemistry from the University of Karlsruhe (KIT), Dr. Ralf Eisenhuth joined Bachem AG in 2008. Over the last decade, he held several positions at Bachem; ranging from process development to leading the large-scale purification of peptides at the Bubendorf site. In his current position as Process Manager Chromatography and Technology Transfer, he is focusing on innovative purification technologies and processes.

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Gunnar Garke is currently working as expert and laboratory manager for preparative HPLC at Bayer AG Pharmaceuticals. He is responsible for the development and upscaling of chromatographic purification processes of small molecule APIs from g to multi-kg scale. In addition Gunnar Garke is also involved in and a consultant for commercial chromatographic manufacturing. He received his Ph.D. in 2000 from the Institute of Biochemical Engineering at the Gesellschaft fuer Biotechnologische Forschung mbH in Braunschweig, Germany. After working for two years in downstream processing of proteins at IBA Biologics GmbH, he went to the Chemical Development of small molecules at Schering AG. In 2008 he moved to Bayer AG in Wuppertal in the same position.

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Massimo Morbidelli received his Laurea in Chemical Engineering at the Politecnico di Milano and PhD at the University of Notre Dame. He is currently Professor at the Politecnico di Milano (Italy) and Professor Emeritus at the ETH Zurich (Switzerland). His main research interest is in the area of biopharmaceutics and specifically on the integrated continuous manufacturing of therapeutic proteins, and its automation and digitalization. Massimo Morbidelli is co-author of more than 750 papers, 23 international patents and six books, including the very recent ones on Continuous Biopharmaceutical Processes (2018), Cambridge University Press, coauthored with D Pfister and L Nicoud and Perfusion Cell Culture Processes for Biopharmaceuticals (2020), Cambridge University Press, coauthored with M Wolf and J-M Bielser. He is the first chemical engineer elected to the Italian Academy of Science (Accademia dei Lincei), serves as the Executive Editor of the ACS journal of Industrial & Engineering Chemistry Research, and is the recipient of: - R.H. Wilhelm Award in Chemical Reaction Engineering by the American Institute of Chemical Engineers, 2005 - Gerhard Damköhler-Medaille of DECHEMA.and VDI-GVC, 2014 - Excellence in Process Development Research Award by the American Institute of Chemical Engineers, 2017 - Separations Science and Technology Award by the American Chemical Society, 2018 - ICB Award, Contributions to Integrated Continuous Biomanufacturing, 2019 - Laurea Honoris Causa, Slovak University of Technology, Bratislava, 2019 In his career he advised more than 100 PhD students. He is a cofounder of ChromaCon Ltd., a spin-off company from his research group, which brings new chromatographic processes (MCSGP-technology) for the purification of proteins and peptides to the market (now acquired by YMC, Japan) and of DataHow Ltd. for the application of data science and machine learning in Biotechnology and specifically in the Biopharma Industry.

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Alírio Rodrigues graduated in Chemical Engineering (1968) at University of Porto (Portugal) and received his Dr. Ing degree (1973) from the Université de Nancy (France). After teaching at the University of Luanda and University of Évora, he joined the Chemical Engineering Department at FEUP in 1976, where he is an Emeritus Professor (since 2013). He has been Visiting Professor at Université Technologie Compiègne, University of Virginia, Universidad de Oviedo and Universidade Federal Ceará. He was the founder of LSRE. His research activities are focused on cyclic adsorption/reaction processes (pressure swing adsorption, simulated moving bed, electric swing adsorption, expanded bed adsorption, parametric pumping) for olefins/paraffins separation, CO2 capture, hydrogen purification, proteins separation, etc., lignin valorization, perfume engineering and microencapsulation. His teaching activities were focused on chemical reaction engineering, separation processes, product engineering and system dynamics and process control. He has supervised more than 60 PhD students and published 740 papers in peer-reviewed journals (h-index of 67; source: Scopus, February 2020), several books and patents.

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Tuomo Sainio is professor in Separation Processes at LUT University (Lappeenranta, Finland) since 2014. He graduated as Doctor of Science (Technol.) in 2005 from the same university. He is a member of the Editorial Board in Adsorption journal. Prof. Sainio’s research focuses on separation processes based on adsorption, ion exchange and reactive extraction. Process design methods for single and multicolumn chromatographic processes are of particular interest. The main applications of his research are in chemical conversion and chromatographic purification of plant based molecules. Another field is hydrometallurgical recovery and purification of valuable metals from primary and secondary sources.

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For over 30 years Dr. Lalit Chordia has pioneered research and development, manufacturing and commercialization of supercritical fluid technology, an environmentally friendly, materials processing technology. Dr. Chordia’s work extends across multiple industries to applications in food, pharmaceuticals, nutraceuticals, chemicals and energy. Some examples of his involvement in supercritical fluid process and equipment technologies over the years are natural pharmaceutical, algae and spice extraction, drug purification and design, coatings, electronics cleaning, cooling, advanced biofuels and a host of other applications and equipment technologies. Dr. Chordia received his bachelor’s degree from IIT Madras and his doctorate from Carnegie Mellon University in 1985, both in Chemical Engineering. In 1982, Dr. Chordia co-founded Suprex Corp., and served as Vice President of Engineering and R&D. He then formed Thar Technologies in 1990. Thar has expanded its operations into multiple industries both domestically and internationally and has earned a reputation as a world leader in high pressure process and equipment technologies, particularly the use of supercritical carbon dioxide, which has zero ozone depletion and net zero global warming potential. Through Dr. Chordia’s leadership of the company, Thar has grown into multiple companies: 1) Thar Instruments, a separations science and equipment company since sold to Waters Corp., 2) Thar Process, a global provider of all-natural food and chemical processing solutions, 3) Thar Pharmaceuticals, a clinical stage drug development company, and 4) Thar Energy, a developer of advanced alternative green energy technology. Dr. Chordia has been the principal investigator on multiple research and development projects, including two prestigious Advanced Technology Program awards through the National Institute of Standards and Technology and multiple Department of Energy projects. Dr. Chordia received the Distinguished Alumnus Award of IIT Madras in 2010 and the Carnegie Science Entrepreneur Award in 2015. In 2002 Dr. Chordia was honored as the SBA’s Small Business Exporter of the Year, and in 2016 he was elected a Fellow to The American Association for the Advancement of Science (AAAS). In 2017, he received the regional Ernest and Young’s Entrepreneur of the Year Award in Technology. Beyond his own business and to remain loyal to his community commitment, Dr. Chordia is a Board Member of Children’s Hospital of Pittsburgh Foundation and serves on the Steering Committee for Sustainable Pittsburgh, is a Co-founder of the US-India Forum and is an Adjunct Research Scientist at the Software Engineering Institute of Carnegie Mellon University. He also serves on the Allegheny County Green Action Team and is an appointee of the U.S. Secretary of Commerce to the Western Pennsylvania District Export Council

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Matthias Franzreb (°1963) received a Ph.D. in chemical engineering from the University of Karlsruhe. During his Ph.D. focussing on ion exchange technology, he worked partly at PennState University, State College, USA under the supervision of Prof. Fred Helfferich. Afterwards he entered the Karlsruhe Institute of Technology and started his work on magnetic micro-adsorbents and their combination with technical scale magnetic separation. In 2002, he finished his Habilitation and in 2009, he was awarded an Extraordinary Professorship by the Karlsruhe Institute of Technology (KIT). Since 2014, he is Associate Director of the Institute of Functional Interfaces at the KIT. His research focuses on novel bioseparation techniques based on physical stimuli (magnetic, electrostatic, and thermal) as well as bioprocess modelling.

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Wolfgang Koehnlein graduated as a Dipl.-Ing. (FH) in Biotechnology at the University of Applied Sciences Weihenstephan in 2001 and started his work life at Roche in Penzberg. The first position included experience in the GMP environment at different scales as well as troubleshooting activities on Äkta Explorer in the small scale. He has been in the late stage purification development since 2003 and has been involved in many collaborations with major vendors during the last 15 years. He likes to work with students and has seen many of them complete their Masters Thesis under his supervision. He is an expert for chromatography in his department and has been working intensively on identifying proper conditions for the application of multimodal resins.

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Hanna Leek With a background in chemical engineering Hanna joined AstraZeneca in 1998. During her career, she has been one of the key players in introducing preparative chromatography to the site in Gothenburg and in the buildup of a large-scale separation laboratory. Hanna has over the past 15 years been driving the introduction of SFC which is today the main purification technique used at the site. Currently she is working as a Director at Early Chemical Development, leading a team of separation scientists with the remit of solving both chiral and achiral separation problems, ranging from small molecules to large peptide conjugates.

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Damien Leinekugel-le-Cocq works at the Process Design and Modeling Division, IFP Energies Nouvelles. He was graduated in chemistry (CPE Lyon, 2001) and he received his Ph.D. in Chemical Engineering from Lyon 1 University in 2004. He has 15 years of experience in separation process development in Refining, Petro Chemistry and Green Chemistry. Particular focus is on chromatographic, adsorption and reaction coupling separation processes. He has contributed to numerous technology development for Eluxyl process (production of paraxylene by Simulated Moving Bed).

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Dr. Gunnar Malmquist is a Senior Principal Scientist within the BioProcess R&D at Cytiva and has over four decades of chromatography experience. His current focus is resin design strategies, Quality by Design, and process analytical technology together with empirical and mechanistic modelling of chromatography data for smarter process development and increased process understanding. Gunnar started his career at Pharmacia Biotech in 1979, working with quality control of chromatographic separation resins. He was later involved in the development of the ÄKTA chromatographic system and the UNICORN software, before moving on 1997 to characterization strategies and design of preparative chromatographic resins. He has been responsible for the design of several of the leading resins on the market, including MabSelect and Capto. Gunnar graduated 1993 from Uppsala University with a Ph. D. in Analytical Chemistry with emphasis on multivariate data analysis applied to chromatographic separations.

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Mikkel is currently CMC Quality Head Italy at GSK vaccines leading the strategic quality support to vaccine development projects. Prior to this role, Mikkel was leading research and technical development of vaccine projects from pre-clinical until commercial launch. Mikkel was trained as analytical chemist and biochemist at the University of Southern Denmark, then moved to the University of Wurzburg as researcher in optical spectroscopy. Before joining GSK Vaccines in 2009, Mikkel worked in a number of biotech and medical technology companies as senior scientist and laboratory head including Becton Dickinson, Hamilton, Tecan and MWG-Biotech.

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Dr Paul O’Shaughnessy is a Senior Principal Scientist at Johnson Matthey’s R&D centre in the UK - JMTC. He joined Johnson Matthey’s Platinum Group Metal Refining Research Group in 2003 following graduate and post-doctoral work as a chemist working on novel metal-ligand chemistries for homogeneous catalysis applications. Since that time his work has focused on separation and purification science and process technologies, specialising in liquid/liquid and solid/liquid separation processes including solvent extraction, chromatography, ion exchange and solid phase extraction. Working in a cross disciplinary commercial research environment he has worked on diverse separation R&D challenges in a wide range of businesses from hydrometallurgy and critical metals recycling to small molecule API and bio-chromatography processes. His work focuses on developing a fundamental understanding of the separation chemistry and applying that understanding to the design and optimisation of separation materials and processes at scale. He has developed patents for novel PGM chromatography separation processes, new solid phase materials for selective PGM and battery materials recycling and was also responsible for successfully introducing chromatography modelling and simulation tools into JMs commercial small molecule API chromatography process development and plant operations. For this work he was awarded the JM global technology innovation prize in 2019.

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Cristina Peixoto working in Animal Cell Technology field since 1996, her PhD contributed to the establishment of several scalable purification processes for complex biopharmaceuticals, mainly virus and virus like particles for vaccine and gene therapy. Since, 2009 she is the Head of the Downstream Process Development lab. Meanwhile Cristina coordinated more than 12 Research Contract Projects with Industrial partners and participated as team member in several Portuguese FCT-funded research projects and EU project consortiums. She is invited lecturer since 2010 in several PhD programs. She published over 64 manuscripts in refereed international journals. More recently, the activities were expanded to stem cells purification and to the development of new purification trains for viral based biopharmaceuticals using advanced materials in integrated and continuous process.

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Gerard Rosse is Vice President at PIC Solution, Inc. and also serves as President at Arrival Discovery LLC. He is a distinguished consultant in medicinal chemistry, laboratory automation and computational sciences for the Pharma industry. Prior, he functioned in scientific and management positions in medicinal chemistry with Dart NeuroScience, Cephalon, Sanofi and Hoffman-La Roche. During his >20 years industrial tenure, he led multidisciplinary teams and invented pre-clinical candidates for CNS, Inflammation, Metabolism, Oncology and Antibacterial Agents indications. Dr. Rosse’s career is also characterized by the implementation of intelligent laboratory automation platforms using Supercritical Fluid Chromatography (SFC) for the manufacturing of small molecules. His current focus is on the development of novel instrumentation and methodologies for using CO2 in extraction and purification at research, pilot and industrial scale. He recently edited a 2-volume book on the applications of SFC in life sciences. Dr. Rosse received the Ph.D. degree in chemistry from the University of Basel in Switzerland and postdoctoral training at Stanford University.

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Antoni Severino is currently Principal Scientist - Global Analytical Sciences at UCB Biopharma Belgium for 8 years. As a Chemical Process Engineer, he completed a PhD in Chemical Engineering at the University of Mons in Belgium. This thesis was entitled “Experimental Study, Dynamic Modelling and Optimization of the Operating Conditions of Chromatographic Separation Processes by Simulated Moving Bed (SMB)”. At UCB, he is responsible for the large scale purification and chiral separation platform within Global Discovery Chemistry Department. His group supports Medicinal Chemistry Research in Braine-l’Alleud (Belgium) and Slough (UK) by HPLC and SFC but also Development and Manufacturing for MCC processes. In addition to daily support within NCE research, Antoni and his team contribute to the development of integrated automated platforms for small/mid-scale achiral purification as part of the global effort to improve digitalization and data management.

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Dorota Antos received a Ph.D. in chemical engineering from Technical University of Wroclaw, Poland. The Ph.D. thesis was awarded by Polish Minister of Education. She completed internships at Politecnico di Milano, Italy, at Max-Planck-Institute in Magdeburg, Germany, and in the frame of Fulbright Grant, at University of Virginia, USA. She habilitated in the field of chromatography and adsorption at Otto-von-Guericke Universitaet in Magdeburg, Germany. In 2012 she was nominated by Polish President as a full professor. Since 2014 she is a chair of Department of Chemical Engineering and Processing, Faculty of Chemistry, of Rzeszow University of Technology, Rzeszow. Since 2016 she is a dean of Faculty of Chemistry.

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P.h.D. student at the University of Porto, attending the Chemical and Biological Engineering doctoral programme.

His research interest is multicomponent chiral separations and other high-added value compounds by simulated moving bed based-processes.

Current project: Complete separation of nadolol stereoisomers using preparative liquid chromatography.

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Xiaoqing BAO is a R&D manager in JOPE Technology Company. JOPE is a specialist in developing processes, Engineering design, and manufacturing equipment for preparative and SMB chromatography eluted either by liquid or by supercritical fluid (SF). Xiaoqing received master degree in Pharmacy from WENZHOU Medical University in China. She was a research assistant in I-Shou University in Taiwan for four years, and learned the application of SF-SMB on fish oil separation. Her current research focus on the separation of active ingredients from nature products, the chiral separation, and the biorefinery for biomass by using SMB or SF-SMB.

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Juliane Diehm studied Bioengineering at the Karlsruhe Institute of Technology (KIT, Germany), where she is now pursuing her PhD at the Institute of Functional Interfaces in the Research Group of Prof. Matthias Franzreb.

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Senior experienced chemist, working 22 years at the Toledo´s Janssen Analytical & HTP team with proficiency in chromatographic techniques at both the Analytical and the Preparative lab. During these years he implemented Open-Access on the Analytical-MS systems and set up the High Throughput Purification-MS platform. Expert on method development, achieving cycle times reductions and increasing the automation on the systems. Knowledgeable on different MS software and on IT workflows with competence to request improvements to vendors or to find new solutions.

Techniques used: HPLC-MS, UHPLC-MS (LRMS and HRMS), GC-MS, SFC-MS, DSC, RP-Flash-RP, HPLC PREP-MS and HPLC-UV.

Publications: 2 (main author), 7 (coauthor); work presented at international congresses.

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Melanie Gerigk completed her MSc in Pharmaceutical Bioprocess Engineering at the Technical University of Munich in 2020. Afterward, she joined Prof. Minceva’s group as a Ph.D. student at the TUM School of Life Sciences, with her main research focus being on the modeling of liquid-liquid chromatographic processes. She is co-author of one paper in Journal of Chromatography A about the separation of minor cannabinoids with liquid-liquid chromatography using the so-called “trapping multiple dual mode”, an operation mode designed for difficult separations of (pseudo-ternary) mixtures and has one paper in progress about the study of nonlinear liquid-liquid chromatography.

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Isabel Harriehausen completed her MSc in Biosystems Engineering at Otto-von-Guericke University in 2017. She is currently working as a doctoral researcher at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg under the supervision of Prof. Andreas Seidel-Morgenstern. Her main research focusses on the coupling of chiral simulated moving bed chromatography with enzymatic racemization for pure enantiomer provision.

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Dr. Juza studied in Stuttgart, Germany, and received his doctorate in Tübingen in the field of enantioselective chromatographic methods in GC, HPLC, SFC and CE. After a post-doctoral stay at the ETH in Zürich with Professor Morbidelli, Mr. Juza headed the preparative HPLC / SMB department for companies in Switzerland and France for over a decade before returning to analytical work in the field of pharmaceuticals again. Since 2015, Mr. Juza is working with Corden Pharma Switzerland as a senior expert for chromatographic separation processes.

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Malte Kaspereit studied Process Engineering a Technical University of Clausthal, Germany. He spent 11 years as researcher and PostDoc at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg, Germany. He obtained his PhD from Otto von Guericke University in Magdeburg under supervision of Andreas Seidel-Morgenstern. In 2011 he became professor at the Institute for Separation Science & Technology, Friedrich-Alexander-University in Erlangen, Germany. MK leads the Advanced Separation Processes group at the Institute. The group develops efficient processes for challenging separations in the production of bulk and fine chemicals, pharmaceuticals, and biological products. MK is member of the SPICA scientific committee.

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Laura Kuger studied Bioengineering at Karlsruhe Institute of Technology (KIT), Germany. She is now working as a associate researcher at the Institute of Functional Interfaces (IFG) and pursuing her PhD in the group of Prof. Matthias Franzreb. Her research focuses on the fractionation of ultra-fine particles by magnetic field controlled chromatography, including process transfer to continuous working systems.

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Ju Weon Lee received a Ph.D. in chemical engineering from Inha University, South Korea. He continued the research at Purdue University, USA and Max Planck Institute in Magdeburg, Germany as a post-doctoral associate. Since 2020 He is a project leader at Otto-von-Guericke University in Magdeburg, Germany.

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Masahiro OGINO is a researcher in ORGANO corporation. ORGANO is a specialist company in water treatment including ultrapure water production for semiconductor. In other hand, ORGANO is a company that have a SMB technology and a lot of achievement installed commercial plant of SMB including food industry. Masahiro OGINO received master degree in Engineering in Tohoku University in Japan. After that, I have been involved in the development of sugar solution purification systems using ion exchange resins and the development of new SMB separation technology at ORGANO. My current research focus on the application of SMB technology to the biopharmaceutical field and the development of new SMB separation methods.

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Albertina Rios, master’s degree on chemical engineering in 2017 by Faculty of Engineering of University of Porto. PhD student in the laboratory LSRE-LCM and working on the area of cyclic adsorption processes. The research focuses on protein separation and purification by simulated moving bed.

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2012-2021: BASF SE – Germany Since 2021: Principal Scientist – Global Expert for Adsorption and Process Scale Chromatography • 2020-2021: Senior Research Engineer – Adsorption and Ion Exchanger • 2018-2020: Global Technology Manager – Health and Nutrition (Omega-3, Ibuprofen, Vitamin E) • 2015-2018: Research Manager (Team Leader) - Adsorption and Ion Exchange • 2012-2015: Research Engineer – Adsorption and Ion Exchange 2010-2011: Post doc at MIT Massachusetts Institute of Technology (USA) and University of Porto (Portugal) Optimization of Simulated Moving Bed Gas Phase with solvent recovery supersrtuctures Supervisor: P.I. Barton and A.E. Rodrigues 2009-2012: Post doc at RWTH Aachen University and Bayer Technology Services (Germany) Continuous LL extractive reaction for in-situ product removal in field of isocyanates Supervisor: T. Müller and T. Müller 2009: Chemical and Biological Engineering PhD from University of Porto (Portugal) Advances in Simulated Moving Bed: New operating modes, New design methodologies and Product development. Supervisor: A.E. Rodrigues and M. Minceva 2008: MBA Finance from University of Porto (Portugal) 2005: Chemical Engineering degree from University of Porto (Portugal)

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Axel Schmidt (Dr.-Ing. In Process Engineering) is a Habilitand at the Institute for Separation and Process Technology at Clausthal University of Technology and has developed his PhD-Thesis on the topic of “Process integration using validated digital twins of liquid-liquid extraction processes for the recovery of metallic, botanical and biotechnological value components “ from October 2015 to the end of 2020 at Clausthal University of Technology at the Institute for Separation and Process Technology. He lectures on Biotechnology as well as Separation Technology and Process Modeling. Mr. Schmidt operates and supervises the laboratory and pilot plant extraction equipment up to 1-2 l/h, i.e. a settler160 l hold-up piloting for cell separation and capture after cultivation at the institute. At the institute Mr. Schmidt developed and established an industrial level extraction process development strategy and continuous processing for biologics and botanicals. His research focuses on process development, integration, intensification, modeling and simulation with a focus on chromatography, distillation, liquid-liquid / solid-liquid extraction, precipitation, crystallization as well as filtration technologies. He is, at the moment, the coworker who has helped to acquire the most project money for the institute from industrial and national grant institutions. His research aims to a methodological answer of upcoming FDA demands on meeting upscale requirements as well as batch or continuous manufacturing process options for biologicals and botanicals with innovative downstream concepts reducing COG significantly.

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Fabian Schmitz studied Pharmaceutical Bioprocess Engineering at the Technical University of Munich, Germany. He spent almost 3 years as a process application engineer for downstream processing at the department Integrated Solutions of Sartorius in Guxhagen, Germany. In the beginning of 2020 he became a scientist and PhD student in the Downstream Processing group of the Advanced BioProcessing department in Corporate Research of Sartorius in Göttingen, Germany. FS is doing his PhD in the field of intensified and continuous downstream processes of biopharmaceuticals under the supervision of Mirjana Minceva at the Technical University of Munich in Germany.

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I joined iBET in 2014 as a Senior Scientist in the Animal Cell Technology Unit (Downstream process development Lab). In 2019, I also integrated the Late-Stage Research and Development unit. Before joining iBET, I completed my PhD in Chemical and Biochemical Engineering with a specialization in numerical process simulation and optimization at Nova University of Lisbon (2014). My studies focused on the development of continuous countercurrent chromatography processes for petrochemical and small molecule applications. Currently, I am focusing on process integration/intensification (up and downstream) and purification of recombinant proteins, cell-based products, extracellular vesicles and virusbased biologics. ORCID iD: https://orcid.org/0000-0003-2959-102X Email: rsilva@ibet.pt Linkedin: www.linkedin.com/in/rjs-silva URL: www.ibet.p

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Kensuke Suzuki is a PhD student in the Department of Materials Process Engineering at Nagoya University, Japan. He has been working in the group of Prof. Yoshiaki Kawajiri for about five years on modeling, uncertainty quantification, and optimization of simulated moving bed chromatography processes. His research interests include pharmaceutical engineering.

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Tatjana is a scientist in the field of mechanistic modeling, researching and developing the GoSilico™ Chromatography Modeling Software at Cytiva. She has extensive background with in vitro and in silico chromatography process development, flow-through operations and scaling. She has studied for a Bachelor and Master of Sciences in Chemical Engineering, and a Dr.-Ing. in biopharmaceutical process development. Tatjana enjoys bringing novel in silico tools to the industry, and searching for an improved understanding of the mechanistic behavior of bioprocessing, enabling rapid process development.

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Florian Vetter, M.Sc. • Since 2019: PhD student at Clausthal University of Technology o Chromatography in biopharmaceutical processes o Integration of continuous chromatography in pharmaceutical processes • 2016-2019: M.Sc. Process Engineering, Clausthal University of Technology

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