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Programme
Indicated times are in CEST timezone.
| Wednesday July 7, 2021 |
| RICT Opening |
| 09:45 | Opening Ceremony |
Prof. Rebecca DEPREZ-POULAIN (UNIVERSITY OF LILLE / INSTITUT PASTEUR OF LILLE, Lille, France)
Prof. Sebastien PAPOT (SCT & UNIVERSITY OF POITIERS, Poitiers, France) |
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| Chemical Biology and Target validation |
| Session Chair |
Dr Boris VAUZEILLES
(INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES, Gif-sur-Yvette, France) |
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| 10:00 | Expanding the Genetic Code - Chemistry in Living Systems (PL01) |
Prof. Kathrin LANG
(ETH ZURICH, Zurich, Switzerland) |
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| 10:30 | Ligand-Directed Labeling of Endogenous Proteins in Live Cells (PL02) |
Prof. Itaru HAMACHI
(KYOTO UNIVERSITY, Kyoto, Japan) |
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| 11:00 | Networking & Exhibition break |
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| Session Chair |
Dr Frédéric SCHMIDT
(INSTITUT CURIE, Paris, France) |
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| 11:30 | Bioorthogonal Protein Activation in Living Systems (PL03) |
Prof. Peng CHEN
(PEKING UNIVERSITY, Beijing, China) |
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| 12:00 | Chemical Biology Tools for Enlightening Therapies (IL01) |
Prof. Olalla VÁZQUEZ
(PHILIPPS-UNIVERSITÄT MARBURG, Marburg, Germany) |
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| 12:20 | End of morning session |
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Poster Session 1
Exhibition
Networking
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| New Modalities in Drug Discovery |
| Session Chair |
Prof. Mélanie ETHEVE-QUELQUEJEU
(UNIVERSITÉ DE PARIS, Paris, France) |
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| 15:00 | Chemical Targeting of DNA and Histone Methylationto Reprogram Cells in Human Diseases: Challenges and Future Perspectives (PL04) |
Dr Paola B. ARIMONDO
(INSTITUT PASTEUR - CNRS, Paris, France) |
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| 16:00 | Networking & Exhibition break |
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| Session Chair |
Dr Maria DUCA
(UNIVERSITY OF CÔTE D'AZUR, Nice, France) |
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| 16:30 | From Simple to Complex in Natural Product Chemistry: Bio-Inspired Strategies to Escape “Flatland” (PL06) |
Prof. Erwan POUPON
(PARIS-SACLAY UNIVERSITY, Châtenay-Malabry, France) |
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| 17:00 | Taming Random Conjugation: a General Approach for Equimolar Linking of Proteins and Payloads (IL02) |
Dr Sergii KOLODYCH
(SYNDIVIA, Strasbourg, France) |
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| 17:20 | End of afternoon session |
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| Thursday July 8, 2021 |
| Case Studies and Disclosures |
| Session Chair |
Dr Pascal GEORGE
(SCT & SCIENTIFIC EXPERT & ADVISER IN DRUG DESIGN AND DEVELOPMENT, Longvilliers, France) |
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| 10:00 | Steroid Sulfatase Inhibition: from Concept to Clinical and Beyond (PL07) |
Prof. Barry POTTER
(UNIVERSITY OF OXFORD, Oxford, United Kingdom) |
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| 10:30 | Recent Advances In Breast Cancer Treatment: Discovery of Amcenestrant (SAR439859), An Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) to Treat ER+ Breast Cancers (PL08) |
Dr Youssef EL AHMAD
(SANOFI, Vitry Sur Seine, France) |
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| 11:00 | Networking & Exhibition break |
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| Session Chair |
Dr Olivier MIRGUET
(EVOTEC, Celle-L’Evescault, France) |
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| 11:30 | Daridorexant - a Dual Orexin Receptor Antagonist (PL09) |
Dr Christoph BOSS
(IDORSIA PHARMACEUTICALS LTD, Allschwil, Switzerland) |
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| 12:00 | Anti-Virulence Agent to Treat S. Aureus Infections (IL03) |
Dr Alessia MICHELOTTI
(BIOVERSYS AG, Lille, France) |
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| 12:20 | End of morning session |
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Poster Session 2
Exhibition
Networking
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| New Tools for Therapeutic Innovation |
| Session Chair |
Prof. Sébastien LECOMMANDOUX
(LCPO, ENSCBP-BORDEAUX INP, Pessac, France) |
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| 15:00 | Multi-Target-Directed Ligands to Combat Neurodegenerative Diseases: All-In-One and One-For-All (PL10) |
Prof. Maria Laura BOLOGNESI
(UNIVERSITY OF BOLOGNA, Bologna, Italy) |
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| 15:30 | Converting Drug Delivery Technologies into Drugs in Unmet Medical Needs (PL11) |
Prof. Jean-Christophe LEROUX
(ETH ZÜRICH, Zürich, Switzerland) |
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| 16:00 | Networking & Exhibition break |
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| Prize Ceremony - Paul Ehrlich Prize |
| 16:30 | Paul Ehrlich Prize Ceremony |
Dr Susana CONDE CEIDE (JANSSEN, Toledo, Spain)
Dr Dominique LESUISSE (SCT & SANOFI, Chilly-Mazarin, France) |
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| 17:25 | End of afternoon session |
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| Friday July 9, 2021 |
| Drugging the Undruggable |
| Session Chair |
Dr Gilles GUICHARD
(UNIVERSITY OF BORDEAUX, Pessac, France) |
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| 10:00 | Targeting Protein-Protein Interactions in Receptor Complexes (PL13) |
Prof. Kristian STROMGAARD
(UNIVERSITY OF COPENHAGEN, Copenhagen, Denmark) |
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| 10:30 | Selecting Targets to Harness the Therapeutic Opportunities Afforded by PROTAC-mediated Protein Degradation (PL14) |
Dr John HARLING
(GLAXOSMITHKLINE, Stevenage, United Kingdom) |
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| 11:00 | Networking & Exhibition break |
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| Session Chair |
Prof. Dominique BONNET
(CNRS-UNIVERSITY OF STRASBOURG, Illkirch, France) |
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| 11:30 | Proteomimetics as Inhibitors of Transcription Factor Complexes (PL15) |
Prof. Tom GROSSMANN
(VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands) |
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| 12:00 | Drugging KRAS with Medchem 2.0 (PL16) |
Dr Darryl MCCONNELL
(BOEHRINGER INGELHEIM, Vienna, Austria) |
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| 12:30 | End of morning session |
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Poster Session 3
Exhibition
Networking |
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| Success Stories |
| Session Chair |
Prof. Philippe BARTHELEMY
(UNIVERSITY OF BORDEAUX, INSERM, Bordeaux, France) |
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| 15:00 | Identification of the Potent, Highly Selective and Orally Bioavailable ATR Inhibitor BAY 1895344 (PL17)
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Dr Franz VON NUSSBAUM
(NUVISAN, Berlin, Germany) |
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| 15:30 | Biomimetic Chemistry of Human RNAi Therapeutics (PL18) |
Dr Muthiah MANOHARAN
(ALNYLAM PHARMACEUTICALS, Cambridge, United States) |
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| 16:00 | Networking & Exhibition break |
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| Prize Ceremony - Pierre Fabre Award Lecture |
| 16:30 | Pierre Fabre Award Ceremony |
Prof. Sebastien PAPOT
(SCT & UNIVERSITY OF POITIERS, Poitiers, France) |
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| 17:25 | Closing Remarks |
Prof. Rebecca DEPREZ-POULAIN
(UNIVERSITY OF LILLE / INSTITUT PASTEUR OF LILLE, Lille, France) |
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