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Programme
Indicated times are in CEST timezone.
| Thursday September 9, 2021 |
| DAY 1 - Morning Session |
| Session Chair |
Prof. Dennis GILLINGHAM
(UNIVERSITY OF BASEL, Basel, Switzerland) |
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| 09:30 | Opening Ceremony |
Prof. Rui MOREIRA (UNIVERSITY OF LISBON, Lisbon, Portugal)
Prof. Dennis GILLINGHAM (UNIVERSITY OF BASEL, Basel, Switzerland) |
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| 09:40 | KL01 - Powerful New Tools for Augmented Medicinal Chemistry |
Dr Werngard CZECHTIZKY
(ASTRAZENECA, Mölndal, Sweden) |
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| 10:10 | OC01 - Design and Synthesis of Novel Benzothiazole-Piperazine Propanamide Derivatives for Multi-Targeted Approach in Alzheimer's Disease Treatment
Winner of the Young Medicinal Chemist Meeting in Turkey
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Ms Bengisu TURGUTALP
(YEDITEPE UNIVERSITY, New York, Turkey) |
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| 10:30 | OC02 - Design and Synthesis of Dual Inhibitors Of DYRK1A/CLK1 Kinases Involved in Neurodegenerative Diseases
Winner of the Young Medicinal Chemist Meeting in France |
Mrs Clementine PESCHETEAU
(ICOA, ORLEANS, France) |
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| 10:50 | OC03 - Towards the Development of ACSL4 Selective Inhibitors to Prevent Ferroptosis in Neurodegenerative Diseases
Winner of the Young Medicinal Chemist Meeting in Belgium (SRC) |
Mr Romain MARTEAU
(LOUVAIN DRUG RESEARCH INSTITUTE, Woluwe-Saint-Lambert, Belgium) |
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| 11:20 | OC04 - Small Organic Molecules to Trigger the Activity of NK Cells
Winner of the Young Medicinal Chemist Meeting in Portugal
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Dr Pedro PINHEIRO
(INSTITUTO SUPERIOR TÉCNICO, Lisboa, Portugal) |
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| 11:40 | OC05 - Novel Hdac6-Selective Inhibitor for Glioblastoma Treatment
Winner of the Young Medicinal Chemist Meeting in Croatia
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Dr Maja BEUS
(INSTITUTE FOR MEDICAL RESEARCH, Durham, United States) |
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| 12:00 | OC06 - Design and Synthesis of Brain Penetrant P38-Alpha Mitogen-Activated Protein Kinase Inhibitors
Winner of the Young Medicinal Chemist Meeting in Germany (DPhG) |
Dr Pierre KOCH
(UNIVERSITÄT REGENSBURG, Germany) |
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Flash Poster Presentations (Odd numbers)
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| 12:20 | FP01 - Electrophilic Warheads for The Assessment of Tractable Cysteines |
Dr Peter ÁBRÁNYI-BALOGH
(RESEARCH CENTRE FOR NATURAL SCIENCES, Budapest, Hungary) |
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| FP03 - Synthesis and In Vitro Evaluation of Novel G6Pd Inhibitors |
Mr Andrea BACCI
(UNIVERSITY OF PISA, Pisa, Italy) |
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| FP05 - Synthesis, Development and Evaluation of a Therapeutic Peptide Conjugate to Protect Biomaterials from Undesired Immune Attack |
Dr Clément BECHTLER
(UNIVERSITY OF BASEL, Wuppertal, Germany) |
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| FP07 - Inhibition of the Protein-“Rna Interaction of Lin28 and Let-7 with Trisubstituted Pyrrolinones |
Ms Lydia BORGELT
(MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY, Dortmund, Germany) |
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| FP09 - Azaaurones as Novel Chemotypes against Mycobacterium Tuberculosis: Sar, Adme Profiling and Photo-Switching Properties |
Mr André CAMPANICO
(I.MED.ULISBOA - FFULISBOA, Lisboa, Portugal) |
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| FP11 - Protac Technology to Investigate Dysregulation of the Ubiquitin-Proteasome System |
Ms Carlotta CECCHINI
(UNIVERSITY OF GENEVA, Geneva, Switzerland) |
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| FP13 - High-Affinity Glycomimetic Ligands for Human Siglec-8 |
Mr Gabriele CONTI
(UNIVERSITY OF BASEL, Basel, Switzerland) |
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| FP15 - Synthesis and Biological Evaluation of Novel Variously Substituted 3-Benzyl-Quinolin-2(1H)-Ones as Potent Agonists of the Gpr55 Receptor |
Mrs Ceni COSTANZA
(UNIVERSITY OF PISA, Empoli, Italy) |
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| FP17 - Design and Synthesis of Novel Androgen Receptor Splice Variant-7 Protacs for the Treatment of Castration-Resistant Prostate Cancer |
Ms Jenny DESANTIS
(UNIVERSITY OF PADUA, Padova, Italy) |
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| FP19 - A Novel Covalent Approach for Stabilising 14-3-3ÎŁ Protein-Protein Interactions |
Ms Marta FALCICCHIO
(UNIVERSITY OF LEICESTER, Leicester, United Kingdom) |
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| 12:40 | End of Morning Session |
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| 13:30 | Poster Session 1 (Odd numbers) & Networking |
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| Roundtable |
| 15:30 | Round Table Discussion: "The Stories Behind the Medicinal Chemists in Industry" |
Ms Helen AYLOTT (GSK, Stevenage, United Kingdom)
Dr Maude GIROUD (F. HOFFMANN-LA ROCHE, Basel, Switzerland)
Dr Toni METSÄNEN (ORION PHARMA, Espoo, Finland)
Dr Fabrizio MICHELI (APTUIT, AN EVOTEC COMPANY, Verona, Italy)
Dr Nikolay SITNIKOV (NUVISAN ICB GMBH, Berlin, Germany)
Dr Fionn O'HARA (F. HOFFMANN-LA ROCHE, Basel, Switzerland) |
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| DAY 1 - Afternoon Session |
| Session Chair |
Dr Michal SHOSHAN
(UNIVERSITY OF ZURICH, Zürich, Switzerland) |
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| 16:45 | OC07 - Metatacs: A Strategy for Metastasis Prevention Through Targeted Fascin Degradation
Winner of the Young Medicinal Chemist Meeting in United Kingdom
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Ms Sarah MEMARZADEH
(UNIVERSITY OF GLASGOW, Glasgow, United Kingdom) |
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| 17:05 | OC08 - Structure Elucidation of Artificial, Self-Assembling Squalene-Conjugates and Β-Peptides
Winner of the Young Medicinal Chemist Meeting in Hungary
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Dr Dora BOGDAN
(SEMMELWEIS UNIVERSITY, Budapest, Hungary) |
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| 17:25 | OC09 - Intracellular Receptor Modulation: Intracellular Ligands for Chemokine Receptors
Winner of the Young Medicinal Chemist Meeting in The Netherlands
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Dr Natalia V. ORTIZ ZACARIAS
(LACDR, LEIDEN UNIVERSITY, Leiden, The Netherlands) |
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| 17:45 | OC10 - A Mating Mechanism to Generate Diversity for the Darwinian Selection Of DNA-Encoded Synthetic Molecules
Winner of the Young Medicinal Chemist Meeting in Switzerland
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Mr Lluc FARRERA SOLER
(UNIVERSITY OF GENEVA, Geneva, Switzerland) |
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| 18:15 | End of Day 1 |
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| DAY 1 - Networking Event |
| 19:00 | EFMC-YSN Virtual Networking Event |
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| Friday September 10, 2021 |
| DAY 2 - Morning Session |
| Session Chair |
Dr Kristina GONCHARENKO
(YOUNG SCIENTISTS NETWORK, Basel, Switzerland) |
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| 09:40 | KL02 - Discovery of Risdiplam (Evrysdi): A Medicine for the Treatment of Spinal Muscular Atrophy
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Dr Hasane RATNI
(F. HOFFMANN-LA ROCHE LTD, Basel , Switzerland) |
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| 10:10 | OC11 - Taming Multiple Contiguous Chiral Centers Through Dynamic Kinetic Resolution
Winner of the Young Medicinal Chemist Meeting in Slovenia
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Dr Andrej Emanuel COTMAN
(FACULTY OF PHARMACY, UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
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| 10:30 | OC12 - Modulators of Coactivator-Associated Arginine Methyltransferase 1 (CARM-1): There and Back Again
Winner of the Young Medicinal Chemist Meeting in Italy
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Dr Ciro MILITE
(UNIVERSITY OF SALERNO, Fisciano, Italy) |
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| 10:50 | OC13 - Hydroxamic Acid-Functionalized Peptide Microarrays for the Study of Zn(II)-Dependent Histone Deacetylases
Winner of the Young Medicinal Chemist Meeting in Denmark |
Dr Carlos MORENO YRUELA
(UNIVERSITY OF COPENHAGEN, Copenhagen, Denmark) |
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| 11:20 | OC14 - Cleistanolate Analogues: Synthesis, Citotoxicity and SAR Study
Winner of the Young Medicinal Chemist Meeting in Serbia
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Dr Jelena KESIC
(FACULTY OF SCIENCES, NOVI SAD, SERBIA, Novi Sad, Serbia) |
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| 11:40 | OC15 - deepSIBA: Chemical Structure-Based Inference of Biological Alterations Using Deep Learning
Winner of the Young Medicinal Chemist Meeting in Greece
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Dr Christos FOTIS
(NATIONAL TECHNICAL UNIVERSITY OF ATHENS, Athens, Greece) |
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| 12:00 | OC16 - ITH15004, A Novel Blood-Brain Barrier-Permeable P2X7 Antagonist: From Drug Design to Pharmacological Applications
Winner of the Young Medicinal Chemist Meeting in Spain
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Dr Francesco CALZAFERRI
(CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Montpellier Cedex 5, France) |
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Flash Poster Presentations (Even numbers)
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| 12:20 | FP02 - From Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands: a New Molecular Alliance at Cb2 Receptor |
Dr Francesca GADO
(UNIVERSITŔ DI PISA, Pisa, Italy) |
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| FP04 - Rational Design of Light-Controlled Bioactive Compounds for Photopharmacology |
Mr Piermichele KOBAURI
(UNIVERSITY OF GRONINGEN, Groningen, The Netherlands) |
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| FP06 - Neuroprotective, Neurotrophic and Anti-Inflammatory Activity of New Synthetic Dhea Neurotrophin Mimetic Derivatives |
Ms Alessia LATORRATA
(NATIONAL HELLENIC RESEARCH FOUNDATION, Athens, Greece) |
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| FP08 - Novel Class of Antinecroptotic Inhibitors: Synthetic Approach and In Vitro Assays |
Mr André LUZ
(FACULTY OF PHARMACY, UNIVERSITY OF LISBON, Lagos, Portugal) |
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| FP10 - Comparative Study of Ck1-Crbn and Ck2-Crbn Complexes using Computational Methods |
Mrs Laura MARQUEZ
(SAN PABLO CEU UNIVERSITY, Alcorcón, Madrid, Spain) |
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| FP12 - Towards Protac-Mediated Degradation of Cbp/Ep300 |
Mr Leonardo PALAFERRI
(UZH, Zurich, Switzerland) |
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| FP14 - Optimization of Compound Metabolic Stability via Shap |
Dr Sabina PODLEWSKA
(MAJ INSTITUTE OF PHARMACOLOGY POLISH ACADEMY OF SCIENCES, Krakow, Poland) |
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| FP16 - In Vivo Photocontrol of Adrenergic Neurotransmission |
Dr Davia PRISCHICH
(INSTITUTE FOR BIOENGINEERING OF CATALONIA (IBEC) , Barcelona, Spain) |
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| FP18 - The E3 Platform: an Investigation of the 3D Pocket Space for Protac Design |
Dr Tommaso PALOMBA
(UNIVERSITŔ DEGLI STUDI DI PERUGIA, Perugia, Italy) |
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| FP20 - Targeting Myeloid Leukemias using Human Dihydroorotate Dehydrogenase Inhibitors based on 2-Hydroxypyrazolo[1,5-A]Pyridine Scaffold: Overcoming of Metabolic Issues |
Dr Chiara VIGATO
(UNIVERSITY OF TURIN, Torino, Italy) |
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| 12:40 | End of Morning Session |
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| 13:30 | Poster Session 2 (Even numbers) & Networking |
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| DAY 2 - Afternoon Session |
| Session Chair |
Dr Laetitia MARTIN
(F. HOFFMANN-LA ROCHE , Basel, Switzerland) |
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| 16:00 | Preparing a Funding Proposal: Setting Yourself up for Success |
Dr Kaycie BUTLER
(BUTLER SCIENTIFIC COMMUNICATIONS, Lausanne, Switzerland) |
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| 16:45 | OC17 - Far-Red Fluorescent DNA Binder Allows Host-Pathogen Interaction Studies of Multidrug-Resistant Bacteria
Winner of the Young Medicinal Chemist Meeting in Germany (GDCh)
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Dr Benedikt HEINRICH
(LABORARZTPRAXIS, Bad Vilbel, Germany) |
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| 17:05 | OC18 - New 5-Arylideneimidazolones in the Ongoing Battle Against Bacterial and Cancer Multidrug Resistance
Winner of the Young Medicinal Chemist Meeting in Poland
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Ms Aneta KACZOR
(JAGIELLONIAN UNIVERSITY, Kraków, Poland) |
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| 17:25 | OC19 - Phosphorylation-Inducing Chimeric Small Molecules
Winner of the Trainee Pre-Conference Forum at the virtual 9th Annual Conference of the International Chemical Biology Society |
Dr Dhanushka MUNKANATTA GODAGE
( BROAD INSTITUTE OF MIT AND HARVARD, Cambridge, United States) |
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| 17:45 | KL03 - Covalent Inhibitors - From Discovery to Functionalization |
Dr Nir LONDON
(THE WEIZMANN INSTITUTE OF SCIENCE, Rehovot, Israel) |
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| 18:15 | Prize Ceremony & Closing |
Prof. Rui MOREIRA
(UNIVERSITY OF LISBON, Lisbon, Portugal) |
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| 18:30 | End of Event |
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